Jagannath University Research Journal

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Volume 5, Issue 1

Title : Unveiling the Dynamics: Interaction of 1NFK Receptor and Active Phytochemicals from BaelFruit

Author : Deepak Garg-a, Dr. Amit Sharma-a, Dr.Pragi-b, Dr.Varun Kumar-b and Dimple Sharma-c

Abstract :

: The purpose of this work is to compare the hepatoprotective role of six active Phytochemicals of Bael—Marmelide, Marmenol, scoparone, 6,7-epoxyaurapetene, and Querectin catechin—as ligands. Techniques: using molecular docking to ascertain how a ligand interacts with its receptor. A lower docking score denotes a more stable protein binding. Findings: Through reacting with residues of amino acids HIS A64, Arg A56, GLY A66, ,ASN A136and  HISA61  of the 1NFK receptor, marmelide, marmenol, scoparone, scopoletin, 6,7-epoxyaurapetene, and querectin catechin were found to have the potential to evolve as a heaptoprotective drug. Conclusions: HIS A64, Arg A56, GLY A66, ,ASN A136and  HISA61  were amino acid residues implicated in ligand protein interactions according to molecular docking.

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